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Sionex Joins Team of CIMIT Medical Experts in Boston Area

Commercialization Avenue for Breakthrough Disruptive Technology

WALTHAM, Mass., November 8, 2004 - Sionex Corporation, a high technology company focused on commercializing breakthrough chemical and biological sensor chips and systems based on its proprietary microDMx™ detection technology, today announced that it has joined the group of leading experts at the Center for Integration of Medicine and Innovative Technology (CIMIT).

CIMIT is a membership organization with a Center at Harvard Medical School composed of leading experts from Partners Healthcare, Massachusetts General Hospital, Beth Israel Deaconess Medical Center, Brigham and Women's Hospital, Children's Hospital Boston, Charles Stark Draper Laboratory and Massachusetts Institute of Technology. CIMIT has a mission to improve patient care by facilitating collaboration of scientists, engineers, and clinicians to catalyze development of innovative technology, emphasizing minimally invasive diagnosis and therapy.

"Sionex's microDMx™ sensor systems will enable the detection and measurement of volatile organics, biomarkers, bacteria, viruses, spores and other biological media resulting in faster, cheaper and less complicated diagnostic protocols," said Lawrence A. Kaufman, Sionex's executive VP, "We have already successfully brought our sensor systems to market with a number of commercial companies for explosive, narcotic and chemical compounds."

Conceived at The Charles Stark Draper Laboratory and exclusively licensed to Sionex for commercialization, the microDMx™ sensor is a chip-based microfabricated technology capable of detecting a wide variety of chemical and biological compounds with great sensitivity and selectivity. Sionex is currently working with a number of companies and collaborators to incorporate its microDMx™ sensors into a wide variety of devices for the detection of chemical & biological warfare agents, explosives, toxic industrial compounds and narcotics.

About Sionex Corporation
Sionex Corporation is a high technology company focused on commercializing breakthrough chemical and biological sensor chips and systems based on its proprietary microDMx™ detection technology. Sionex maintains its worldwide headquarters and laboratories in Waltham, Massachusetts, close to Boston with its commercial, technology and communications infrastructure. The Company is privately held and was founded in 2001 with patented technology exclusively licensed from The Charles Stark Draper Laboratory. Additional information about Sionex Corporation is available at www.sionex.com.

microDMx™ is a US trademark of Sionex Corporation.

EDITORIAL CONTACTS:

Anthony D. Bashall, Sionex Corporation
+1 (781) 457-5407
abashall@sionex.com

Agency Contact:
Doug Forsyth, Alchymia Communications for Sionex
+1 (541) 482-8744
df@alchymiacomm.com

Forward-looking Statement
Some statements in this announcement constitute forward-looking statements. Forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Sionex Corporation to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. There can be no assurance that the forward-looking statements included in this announcement will prove to be accurate. In light of the significant uncertainties inherent in the forward-looking statements included herein, the inclusion of this information should not be regarded as a representation by the Company or any other person that the objectives and plans of the Company will be achieved.